OpenEvidence, a Miami, Florida–based startup that provides a medical AI platform, has raised $250 million in a Series D funding round, valuing the company at $12 billion.
Investors
The round was co-led by Thrive Capital and DST Global, with participation from a broad group of existing institutional investors.
Founded in 2010, Thrive Capital is a venture capital firm that builds and invests in internet, software, and technology-enabled companies. Headquartered in New York City, the firm manages approximately $25 billion in assets as of November 2024.
DST Global is a growth equity and venture capital firm specializing in late-stage investments in high-growth internet and technology companies. Founded in 2009, DST Global has backed several prominent technology platforms, often prior to or around their public listings.
OpenEvidence Use of Funds
The funding will be used to invest heavily in the R&D and compute costs associated with the multi-AI agentic architecture of OpenEvidence.
About OpenEvidence
Founded by Daniel Nadler, OpenEvidence is an AI-powered medical search engine designed exclusively for clinicians. It provides real-time, citation-linked answers sourced solely from trusted, peer-reviewed medical literature. OpenEvidence has established exclusive AI partnerships with leading medical institutions, including the New England Journal of Medicine, the American Medical Association, and the National Comprehensive Cancer Network. Headquartered in Miami, Florida, OpenEvidence is used daily by more than 40% of U.S. physicians across over 10,000 hospitals and medical centers.
Funding Details
Company: OpenEvidence
Raised: $250.0M
Round: Series D
Funding Date: January 2026
Lead Investors: Thrive Capital, DST Global
Additional Investors: Sequoia, Google Ventures, Nvidia, Kleiner Perkins, Blackstone, Coatue, ICONIQ, Greycroft, Breyer Capital, BOND, Craft Ventures, Mayo Clinic, and others
Company Website: https://openevidence.com/
Software Category: Healthcare AI / Medical Search
Source: https://www.businesswire.com/news/home/20260121029132/en/